Nuclear Membranes of Cultured Mammalian Cells in the Period Preceding Dna Synthesis
نویسندگان
چکیده
When kidney cells are cultured directly from the rabbit, the nuclear membranes undergo a change that can be measured as an increase in electrophoretic mobility. The change appears to begin immediately upon culture and is maximal 2 hours later, after which the mobility remains constant at the elevated level. Actinomycin D and p-fluorophenylalanine, but not EDTA or ionizing radiation, suppress the increase in nuclear electrophoretic mobility. With synchronously growing L cells, no change was detected in nuclei from cells taken during various parts of the division cycle.
منابع مشابه
Nuclear Membranes of Cultured Mammalian Cells
When kidney cells are cultured directly from the rabbit, the nuclear membranes undergo a change that can be measured as an increase in electrophoretic mobility. The change appears to begin immediately upon culture and is maximal 2 hours later, after which the mobility remains constant at the elevated level. Actinomycin D and p-fluorophenylalanine, but not EDTA or ionizing radiation, suppress th...
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ورودعنوان ژورنال:
- The Journal of Cell Biology
دوره 25 شماره
صفحات -
تاریخ انتشار 1965